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Edelblum Lab

 IBD research laboratory at Mount Sinai School of Medicine studying immune/epithelial interactions to better understand the underlying causes of Crohn's disease and discover potential new areas for therapeutic development

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3.1 million Americans


Crohn's disease and ulcerative colitis affect 1.3% of the population with 70,000 new cases diagnosed every year. IBD is caused by a combination of genetic and environmental factors that lead to an abnormal immune reaction to the normal bacteria found in the intestine.




We're excited to welcome to the lab Ananya Parthasarathy as a ISMMS Master's student and Dr. Irving Martínez-Vargas as a postdoc. Keep an eye out for their new studies, coming soon!

October 2023

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In a preprint available on bioRxiv, we show multiple layers of dysregulation within the gamma delta IEL compartment prior to the onset of Crohn's disease-like ileitis suggesting that altered gamma delta IEL biology may be a useful biomarker for disease relapse or response to therapy.

August 2023

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Summer sendoff for Anika and Jacob!

We had a great summer working with two outstanding high school students, Anika Bhatnagar and Jacob Warner. Thanks for commuting into Manhattan over the summer to learn about gamma delta T cells and IBD!

August 2023

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Sara's new review focusing on gamma delta IEL immunometabolism is available through open access in

Discovery Immunology

August 2023

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Are you an incoming graduate student at ISMMS? Are you looking for a mucosal immunology lab that incorporates basic and translational research? Do you appreciate a lab that supports a healthy work/life balance? Do you like snacks? If so, we might be the lab for you! Contact us below about a rotation.

Summer 2023



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