projects
3.1 million Americans
LIVE WITH INFLAMMATORY BOWEL DISEASE
Crohn's disease and ulcerative colitis affect 1.3% of the population with 70,000 new cases diagnosed every year. IBD is caused by a combination of genetic and environmental factors that lead to an abnormal immune reaction to the normal bacteria found in the intestine.
news
Check out our latest publication in Journal of Immunology showing that type I IFN promotes gamma delta IEL antimicrobial responses through TCR-independent and -dependent mechanisms. Congrats to Matt on this highly mechanistic study!
September 2024
After a successful defense, we're excited to see what discoveries in immune/epithelial biology Natasha will make during her postdoc with Chuck Parkos & Asma Nusrat at UMichigan.
October 2024
We're excited to welcome our new lab manager Noah Grunberg, Sayra Garcia (postdoc) and Tingting Li (instructor) to the wonderful world of gamma delta IELs!
October 2024
Thank you to everyone who donated or joined us at the NYC Take Steps Walk! With your help we raised enough to support one undergraduate summer research fellowship!
June 2024
In a preprint available on bioRxiv, we show multiple layers of dysregulation within the gamma delta IEL compartment prior to the onset of Crohn's disease-like ileitis suggesting that altered gamma delta IEL biology may be a useful biomarker for disease relapse or response to therapy.
August 2023