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Edelblum Lab

 IBD research laboratory at Mount Sinai School of Medicine studying immune/epithelial interactions to better understand the underlying causes of Crohn's disease and discover potential new areas for therapeutic development

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3.1 million Americans

LIVE WITH INFLAMMATORY BOWEL DISEASE

Crohn's disease and ulcerative colitis affect 1.3% of the population with 70,000 new cases diagnosed every year. IBD is caused by a combination of genetic and environmental factors that lead to an abnormal immune reaction to the normal bacteria found in the intestine.

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We're ready to rally and be part of the large movement to ensure that biomedical research continues to thrive in the United States. Come join us in Washington Square Park and show your support of NIH, CDC, NSF and the other government agencies that fund the basic science research that is fundamental to human health!

March 7, 2025

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We're excited to welcome our Ben Pundyk (clinical coordinator) and Joana Barros Martins to Mount Sinai!

March 2025

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Ananya receives APS GIL Research Recognition Award

Congrats to Ananya for being named an APS GIL Research Recognition Award winner! You can catch her short talk on CD47 and gamma delta IEL motility at the Trainee Symposium during the APS Summit in April.

February 2025

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Sayra joins the Translational Immunology T32

As the newest appointee on Mount Sinai's Translational Immunology T32, we look forward to great things as Sayra works to understand the contribution of purinergic signaling on gamma delta IELs.

February 2025

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Check out our latest publication in Journal of Immunology  showing that type I IFN promotes gamma delta IEL antimicrobial responses through TCR-independent and -dependent mechanisms. Congrats to Matt on this highly mechanistic study!

September 2024

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In a preprint available on bioRxiv, we show multiple layers of dysregulation within the gamma delta IEL compartment prior to the onset of Crohn's disease-like ileitis suggesting that altered gamma delta IEL biology may be a useful biomarker for disease relapse or response to therapy.

August 2023

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Copyright 2017 Karen Edelblum

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